ONSIOR - robenacoxib- anti-inflammatory for the treatment of acute pain and inflammation for dogs

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Onsior 40 mg is an anti-inflammatory for the treatment of acute pain and inflammation associated with musculoskeletal disorders in dogs.

What is Onsior?

Onsior contains robenacoxib, which belongs to a class of drugs that reduce fever, pain and inflammation. It is available in tablet form, in five different concentrations (6 mg for cats and 5 mg, 10 mg, 20 mg and 40 mg for dogs).

What is the dose of Onsior?

Body weight of the dog (kg)

Number of tablets by size

5 mg

10 mg

20 mg

40 mg

2.5 to < 5

1 tablet

5 to < 10

1 tablet

10 to < 20

1 tablet

20 to < 40

1 tablet

40 to 80

2 tablets

What is Onsior used for?

In cats, Onsior tablets are used in the treatment of acute pain and inflammation associated with musculoskeletal disorders (muscle and bone problems).

In dogs, Onsior tablets are used in the treatment of pain and inflammation associated with chronic osteoarthritis (a long-term disease that causes pain in the joints).

Tablets are administered once a day, at the same time, at a dose of 1 mg per kilogram body, with a dose interval of between 1-2 mg / kg.

Treatment in cats is limited to six days. Dogs should be treated for as long as it takes.

How does Onsior work?

The active substance in Onsior, robenacoxib, belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). This works by blocking an enzyme called cyclo-oxygenase 2 (COX-2). This enzyme is involved in the synthesis of substances called prostaglandins, which are involved in pain and inflammation. By blocking the synthesis of prostaglandins, robenacoxib reduces pain and inflammation caused by musculoskeletal disorders, surgery or osteoarthritis.

How was Onsior studied?

Onsior has been studied on laboratory animals, as well as through "clinical studies" with cats and dogs treated in veterinary offices and clinics in Europe. In clinical trials, Onsior has been compared with other veterinary medicines containing NSAID (ketoprofen, meloxicam or carprofen). Studies have involved cats and dogs of different ages, sexes and breeds.

The tablets were studied over five or six days in cats with acute musculoskeletal disorders and for up to one year in dogs with osteoarthritis.

The tablets were given to the animals once or twice a day. The effectiveness was determined on the basis of the examinations carried out by a veterinarian and the evaluations made by the owner of the animal.

What benefits did Onsior show during the studies?

Onsior tablets taken once a day reduced pain and improved mobility in both cats and dogs. Onsior was as effective as the NSAID comparator.

What are the risks associated with Onsior?

The side effects of Onsior are similar to those seen in other NSAIDs. The most common side effects of tablet administration and injectable solution are mild and transient effects in the stomach and intestine, manifested in the form of vomiting, soft feces and diarrhea. In 1% to 10% of dogs, there was an increase in liver enzyme levels following long-term tablet treatment. The injectable solution can also cause pain at the injection site. For the full list of all reported side effects associated with Onsior, see the prospectus.

Onsior tablets should not be given to dogs or cats with existing stomach and bowel disorders, such as stomach ulcers or bleeding, or to dogs with liver disorders. They should not be given to pregnant animals, which breastfeed puppies or cats or are used for mating or which are hypersensitive (allergic) to robenacoxib or any other ingredient of this medicine.

It should be administered carefully to cats and dogs known to have heart or kidney problems and to cats with liver problems.

Onsior should not be taken with other NSAIDs or glucocorticoids.

What are the precautions for the person taking the medicine or coming into contact with the animal?

Wash your hands after taking a dog or cat.

In case of accidental ingestion of tablets, especially in young children, seek immediate medical help and show the doctor the leaflet or label.

In pregnant women, especially those in advanced pregnancy, accidental ingestion of Onsior can be dangerous for the unborn child.